Center for Reproductive Health Research Studies

If you are unsure about what studies you qualify for, simply email us at [email protected]. Alternatively, explore different UCSF studies at clinicaltrials.ucsf.edu

I'm interested in participating!


Intrauterine Insemination (IUI) Studies

 

 

In Vitro Fertilization (IVF) Studies

3M Study| Aneuploidy Rates and Morphokinetic Parameters in Sibling Embryos Cultured in Distinct Culture Media

Status: Active, Enrolling
This clinical trial is to determine whether the use of a different culture media is associated with differences in embryo quality and aneuploidy. This study aims to compare Aneuploidy/Embryo Quality in sibling embryos cultured in distinct media as well as breached on D3 versus at the Blastocyst stage. 

You may be eligible if you are: a male-female couple, aged 18 years or older, and undergoing IVF with planned Preimplantation Genetic Screening (PGS)

 

Flor Juarez
Clinical Research Coordinator
415-514-6387

Mitchell Rosen MD
Principal Investigator

 


APPOSE Study | Assessment and Prevention of Pain During Ovarian Stimulation in Patients with Endometriosis

Status: Active, Enrolling
Endometriosis is an estrogen dependent disease present in 25-35% of infertile women. When treating infertility controlled ovarian hyperstimulation leads to development of multiple follicles and considerable rise in serum estradiol concentration, patients and providers must consider the posible risk of disease and symptom progression related to ovarian hyperstimulation. The purpose of this study is to evaluate the impact of this hyperstimulation on symptoms related to endometriosis using patient surveys, and to evaluate the impact of Letrozole use during this stimulation with respect to symptoms related to endometriosis, embryo quality, and pregnancy rates. 

You may be eligible if you are: diagnosed with Endometriosis and are undergoing fertility treatments

Kaitlyn Wald MD
REI Fellow
415-353-7475
[email protected]

Marcelle Cedars MD
Principal Investigator

 


CHIP Study | Sperm Selection by Microfluidic Separation Improves Embryo Quality (CHIP)

Status: Active, Enrolling
This is a randomized controlled trial of couples with a history of poor embryo quality undergoing a repeat in vitro fertiliation (IVF) cycle for unexplained infertility. Couples will be randomized to sperm selection by the clinical standard of centrifugation and density-gradient processing compared to the microfluidic sperm sorting chip.

You may be eligible if you are: a male-femal couple, aged 18 years or older, and undergoing IVF or ICSI treatment

Flor Juarez
Clinical Research Coordinator
415-514-6387
[email protected]

Mitchell Rosen MD
Principal Investigator

Clinic Trials Website
 


CLeAR Study | Cytokines, Lipids, and Reproduction (CLeAR) 

Status: Active, Enrolling
The CLeAR study is investigating markers of inflammation and reproductive health. Inflammation may influence human fertility and we would like to know more about these factors and evaluate the impact of these markers on various stages of reproduction. Participants will be asked for a short blood draw and follicular fluid collection (typically discarded during IVF) during their retrieval procedure. 

You may be eligible if you are: female, aged 18-43 years old, and undergoing in vitro fertilization (IVF) treatment

Jamie Corley
Clinical Research Coordinator
415-502-2557
[email protected]

 

Martha Noel MD
Principal Investigator

 

 

Victor Fujimoto MD
Principal Investigator

 

 

 

 


DESCRT Study | Developmental Epidemiological Study of Children born through Reproductive Technology

Status: Active, Enrolling
Despite the rise in the number of births from fertility treatments, there are limited long-term data on health of the offspring. The purpose of the study is to establish an epidemiological cohort of almost 4,000 pregnancies to address critical public health questions regarding potential metabolic risk to children conceived through fertility treatments.

You may be eligible if you: have previously/are currently receiving fertility treatment from UCSF Center for Reproductive Health 

Panayota Rigas
Clinical Research Coordinator
415-502-2557
[email protected]

 

Marcelle Cedars MD
Principal Investigator

 

Bria Donaldson
Clinical Research Coordinator
415-353-7475
B[email protected]

 

Zakia Young
Clinical Research Coordinator
415-502-2557
[email protected]

 

Meghan Beard
Clinical Research Coordinator
415-502-4492
M[email protected]

 

clinical trials Website


FEM Differences Study | Female Estrogen Metabolism (FEM) Differences Study

Status: Active, Enrolling
Women have variable amounts of estrogen produced from the growing follicles that circulates in their blood as they undergo ovarian stimulation. Higher studies suggest this difference may be related to how women metabolize estrogen. This matters because it effects how much hormone goes in circulation and may have implications on how effective medications are, as well as how many medication side effects women feel. Our goal will be to determine, if metabolize difference are present, and if so, to learn why these differences ocur. 

You may be eligible if you are: Female, 18 years or older, and undergoing ovarian stimulation for elective oocyte cryopreservation or in vitro fertilization.

 

 

Amy Wijekoon MD
REI Fellow
415-353-7475
[email protected]

Victor Fujimoto MD
Principal Investigator

 

Amanda Adeleye MD
REI Fellow
415-353-7475
[email protected]

 

 


hESC Study | Generation and study of clinical-grade Human Embryonic Stem Cell lines

Status: Active, Enrolling
The study is enrolling UCSF CRH patients willing to donate embryos created during the IVF cycle that are of low quality and therefore cannot be used for treatment. Embryos to use in this project would normally be discarded because their quality indicates that they cannot implant and subsequently cannot give rise to pregnancy. The overall goal of the study is to develop cell-based therapies for diabetes. 

You may be eligible if you are: female (or assigned female at birth), aged 18-41, undergoing IVF treatment at UCSF Center for Reproductive Health, and not using sperm or ovum donor samples

Bryn Carlson
Clinical Research Coordinator
415-535-7186
[email protected]

 

Hakan Cakmak MD
Principal Investigator

 

Lilian Lau
Clinical Research Coordinator
415-535-7186
[email protected]

 

Michael McMaster PhD
Principal Investigator
 

 

Susan Fisher PhD
Principal Investigator
 

 

 


INVOcell | Comparing Intra-Vaginal Culture of Embryos using INVOcell Device to In-vitro Culture of Embryos

Status: Active, Enrolling
The purpose of this study is to evaluate implantation rate with intra-vaginal culture with the INVOcell devise versus traditional IVF while using minimal stimulation protocols. 

You may be eligible if you are: female (or assigned female at birth), aged 18-37, and experiencing one or more years of infertility

Nikolaus Lenhart
Senior Clinical Research Coordinator
415-502-2555
N[email protected]

Marcelle Cedars MD
Principal Investigator

Clinic Trials Website