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Reproductive Health Management Research

Throughout the lifespan, our hormones undergo many changes and can serve multiple purposes. It is well documented that a healthy endocrine system can protect and extend lifespans. However, when there are irregularities in the endocrine system, many other systems may be disrupted. At CRH, our faculty study fluctuations in the endocrine system and examine the effects of these fluctuations throughout life including the impact on mood, sleep, diabetes and cardiovascular risk.

Status: Active, Enrolling

GEAR Study | Gender Expansive Attitudes about Reproductive Health Study

Currently, there are few studies (and none in the United States) that seek to describe the impact of expanding fertility services on the transgender community and their quality of life. The GEAR study will be one of the first of its kind to explore the impact of fertility options on quality of life among transgender, non-binary, and non-conforming people.

You may be eligible if you are: you identify as transgender or gender non-binary, and aged 18 years or older

Headshot of Evelyn Mok-Lin, MD - Principle Investigator
Evelyn Mok-Lin, MD
Principle Investigator

Status: Active, Not Enrolling New Participants

OVA.CV Study | Longitudinal Evaluation of Ovarian Aging and Cardiovascular Risk

The Ovarian Aging (OVA) cohort is the largest and most ethnically diverse, community-based cohort available that can be used to determine the race/ethnic and behavioral determinants of ovarian aging and its association with CVD risk in a young cycling population. The purpose of the study is to use a longitudinal approach to evaluate markers of ovarian and cellular aging as predictors of CVD, and potentially develop new risk-reduction strategies.

We are currently not accepting any new participants.

Headshot of Marcelle Cedars, MD - Principal Investigator
Marcelle Cedars, MD
Principal Investigator
Headshot of Melissa Rios - Research Coordinator
Melissa Rios
Research Coordinator

Headshot of Lisa Kao - Research Coordinator
Lisa Kao
Research Coordinator
Headshot of Marika Stanford-Moore - Project Manager
Marika Stanford-Moore
Project Manager

Status: Active, Enrolling

START Study

The START study (Sensor Technology Assessment of Reproductive Targets) intends to use new technology to solve old problems in reproductive medicine. We will leverage continuous physiological data collected from a wearable device (the oura ring) to open a new window onto the menstrual cycle and to develop algorithms that predict ovulation and pregnancy onset, and to better understand a variety of reproductive disorders. This interdisciplinary, multi-center, private-public partnership is poised to generate impactful discoveries in reproductive medicine and enable new tools for women's reproductive autonomy. 

Currently eligible to healthy (not seeking fertility treatment) 18-42 year olds with regular menstrual cycles. 

Headshot of Eleni Jaswa, MD - Principle Investigator
Eleni Jaswa, MD
Principle Investigator
Headshot of Elissa Lyn Apiag - Research Coordinator
Elissa Lyn Apiag
Research Coordinator
Status: Active, Enrolling

The EDGE Study: Egg Donor Gained Experiences Study

There has been a lack of literature describing both short and long-term adverse consequences of egg donation. This study hopes to 1) characterize the medical, emotional, and psychosocial impact of oocyte donation following donation, 2) to describe one's subjective experience with the process, 3) to assess the potential impact this decision had on one's own medical history, and 4) to evaluate individual factors associated with the above reflections. Participants will be recruited from UCSF and a private fertility clinic in San Francisco. All participants will receive a questionnaire and we hope results will inform improvements in the long-term care of oocyte donors.  You may be eligible if you are: a prior UCSF egg donor (1/2009-1/2020) and not actively undergoing egg donation.

Headshot of Dr. Lauri Pasch - Principal Investigator
Dr. Lauri Pasch
Principal Investigator
Headshot of Eleni Jaswa, MD - Principal Investigator
Eleni Jaswa, MD
Principal Investigator
Headshot of Jerrine R. Morris - REI Fellow
Jerrine R. Morris
REI Fellow
Headshot of Lisa Kao - Clinical Research Coordinator
Lisa Kao
Clinical Research Coordinator