Polycystic Ovarian Syndrome Studies
MINDD Study | Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Status: Active, Enrolling
This clinical trial explores new options for treating depressed mood in women with PCOS, low Vitamin D and insulin resistance. Participants will complete psychological questionnaires and have blood testing. They will be randomly assigned to one of two treatments (Vitamin D or Metformin). Mood and blood testing is repeated after the 12-week trial, and participants will have an individualized follow-up visit with the study doctor to wrap-up.
You may be eligible if you are: female (or assigned female at birth), aged 18-45, diagnosed with PCOS, presence of insulin resistance and low Vitamin D
Eleni Greenwood MD
Principal Investigator
Heather Huddleston MD
Principal Investigator
clinical trials Website
For more information or additional PCOS related studies, please visit our PCOS clinic website.
PCOS and Elagolix Study | Investigating the Safety and Efficacy of Elagolix in Women with PCOS
Status: Active, Enrolling
Elagolix is currently approved for the treatment of Endometriosis and could potentially alleviate symptoms associated with PCOS in this study, we are attempting to monitor the effects of various doses of Elagolix to see whether it is a viable option for women diagnosed with PCOS.
You may be eligible if you are: female (or assigned female at birth), aged 18-35, are not planning to get pregnant for the duration of the study (approximately 42 weeks), and diagnosed with PCOS
Heather Huddleston MD
Principal Investigator
PCOS Clinic Website
For more information or additional PCOS related studies, please visit our PCOS clinic website.
PCOS Exercise Study | Effects of Exercise on Polycystic Ovary Syndrome
Status: Active, Enrolling
This study is determining which type of exercise, vigorous for a short duration or moderate for a longer duration, will help patients with PCOS most in improving insulin resistance, BMI, metabolic profiling, and mood symptoms. Participants will be assigned to one of the two exercise regimens, meet with an exercise physiologist for a one-hour training session, and be provided with a FITBIT Fitness Tracker for the duration of the study.
You may be eligible if you are: female (or assigned female at birth), aged 18-50, diagnosed with PCOS and presence of insulin resistance
Martha Noel MD
Principal Investigator
PCOS Clinic Website
For more information or additional PCOS related studies, please visit our PCOS clinic website.
Paleo Diet Study | Paleo Versus Healthy ADA Diets for Treatment of Polycystic Ovarian Syndrome (PCOS)
Status: Active, Enrolling
This study is evaluating the effects of specific diets on the regulation of menstrual cycles in PCOS patients to help improve fertility treatments for women with PCOS. Participants will follow a paleolithic-type diet or a health ADA-recommended diet to see if either one can help regulate menstrual cycles. Participation will be supported by visits with a diet coach, social media activity, and teleconferences with investigators.
Additional information about the PCOS Paleo Diet study can be found at the following websites:
You may be eligible if you are: female (or assigned female at birth), aged 18-40, and diagnosed with PCOS
Heather Huddleston MD
Principal Investigator
clinical trials Website
For more information or additional PCOS related studies, please visit our PCOS clinic website.
PCOS Tissue Bank & Longitudinal Study
Status: Active, Enrolling
The purpose of this study is to explore the relationship between genetic and environmental factors that may explain PCOS. We will use information collected during visits to our PCOS clinic and the family history of PCOS patients to learn about the causes and effects of PCOS.
You may be eligible if you are: female (or assigned female at birth), aged 18 years or older, and diagnosed with PCOS
Heather Huddleston MD
Principal Investigator
PCOS Clinic Website
For more information or additional PCOS related studies, please visit our PCOS clinic website.
